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Design And Analysis Of Clinical Trials


Author : Shein-Chung Chow
language : en
Publisher: John Wiley & Sons
Release Date : 2008-12-04


PDF Download Design And Analysis Of Clinical Trials Books For free written by Shein-Chung Chow and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-12-04 with Mathematics categories.




Foundations Of Time Series Analysis And Prediction Theory


Author : Mohsen Pourahmadi
language : en
Publisher: John Wiley & Sons
Release Date : 2001-06


PDF Download Foundations Of Time Series Analysis And Prediction Theory Books For free written by Mohsen Pourahmadi and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-06 with Mathematics categories.


The author emphasizes the foundation and structure of time series and backs up this coverage with theory and application.".

Clinical And Translational Science


Author : David Robertson
language : en
Publisher: Academic Press
Release Date : 2009-03-02


PDF Download Clinical And Translational Science Books For free written by David Robertson and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-03-02 with Medical categories.


Clinical or translational science is the field of study devoted to investigating human health and disease, interventions and outcomes for the purposes of developing new treatment approaches, devices, and modalities to improve health. New molecular tools and diagnostic technologies based on clinical and translational research have lead to a better understanding of human disease and the application of new therapeutics for enhanced health. Clinical and Translational Science is designed as the most authoritative and modern resource for the broad range of investigators in various medical specialties taking on the challenge of clinical research. Prepared with an international perspective, this resource begins with experimental design and investigative tools to set the scene for readers. It then moves on to human genetics and pharmacology with a focus on statistics, epidemiology, genomic information, drug discovery and development, and clinical trials. Finally, it turns to legal, social, and ethical issues of clinical research concluding with a discussion of future prospects to provide readers with a comprehensive view of the this developing area of science. Clinical research is one of the fastest growing fields in private practice and academic medicine with practical biological, physiological, cellular, and therapeutic applications Contributions from international leaders provide insight into background and future understanding for clinical and translational science Provides the structure for complete instruction and guidance on the subject from fundamental principles, approaches and infrastructure to human genetics, human pharmacology, research in special populations, the societal context of human research, and the future of human research

A Course In Time Series Analysis


Author : Daniel Peña
language : en
Publisher: John Wiley & Sons
Release Date : 2011-01-25


PDF Download A Course In Time Series Analysis Books For free written by Daniel Peña and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-01-25 with Mathematics categories.


New statistical methods and future directions of research in time series A Course in Time Series Analysis demonstrates how to build time series models for univariate and multivariate time series data. It brings together material previously available only in the professional literature and presents a unified view of the most advanced procedures available for time series model building. The authors begin with basic concepts in univariate time series, providing an up-to-date presentation of ARIMA models, including the Kalman filter, outlier analysis, automatic methods for building ARIMA models, and signal extraction. They then move on to advanced topics, focusing on heteroscedastic models, nonlinear time series models, Bayesian time series analysis, nonparametric time series analysis, and neural networks. Multivariate time series coverage includes presentations on vector ARMA models, cointegration, and multivariate linear systems. Special features include: Contributions from eleven of the worldâ??s leading figures in time series Shared balance between theory and application Exercise series sets Many real data examples Consistent style and clear, common notation in all contributions 60 helpful graphs and tables Requiring no previous knowledge of the subject, A Course in Time Series Analysis is an important reference and a highly useful resource for researchers and practitioners in statistics, economics, business, engineering, and environmental analysis. An Instructor's Manual presenting detailed solutions to all the problems in he book is available upon request from the Wiley editorial department.

Models For Probability And Statistical Inference


Author : James H. Stapleton
language : en
Publisher: John Wiley & Sons
Release Date : 2007-12-14


PDF Download Models For Probability And Statistical Inference Books For free written by James H. Stapleton and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-12-14 with Mathematics categories.


This concise, yet thorough, book is enhanced with simulations and graphs to build the intuition of readers Models for Probability and Statistical Inference was written over a five-year period and serves as a comprehensive treatment of the fundamentals of probability and statistical inference. With detailed theoretical coverage found throughout the book, readers acquire the fundamentals needed to advance to more specialized topics, such as sampling, linear models, design of experiments, statistical computing, survival analysis, and bootstrapping. Ideal as a textbook for a two-semester sequence on probability and statistical inference, early chapters provide coverage on probability and include discussions of: discrete models and random variables; discrete distributions including binomial, hypergeometric, geometric, and Poisson; continuous, normal, gamma, and conditional distributions; and limit theory. Since limit theory is usually the most difficult topic for readers to master, the author thoroughly discusses modes of convergence of sequences of random variables, with special attention to convergence in distribution. The second half of the book addresses statistical inference, beginning with a discussion on point estimation and followed by coverage of consistency and confidence intervals. Further areas of exploration include: distributions defined in terms of the multivariate normal, chi-square, t, and F (central and non-central); the one- and two-sample Wilcoxon test, together with methods of estimation based on both; linear models with a linear space-projection approach; and logistic regression. Each section contains a set of problems ranging in difficulty from simple to more complex, and selected answers as well as proofs to almost all statements are provided. An abundant amount of figures in addition to helpful simulations and graphs produced by the statistical package S-Plus(r) are included to help build the intuition of readers.

Models For Investors In Real World Markets


Author : James R. Thompson
language : en
Publisher: John Wiley & Sons
Release Date : 2009-09-25


PDF Download Models For Investors In Real World Markets Books For free written by James R. Thompson and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-09-25 with Mathematics categories.


* Considers neoclassical models in light of results that can go wrong with them to bring about better models. * Questions the assumption that markets clear quickly. * Offers a timely examination of the LTCM collapse. * Written by a group of well-respected and highly qualified authors.

Combinatorial Methods In Discrete Distributions


Author : Charalambos A. Charalambides
language : en
Publisher: John Wiley & Sons
Release Date : 2005-06-24


PDF Download Combinatorial Methods In Discrete Distributions Books For free written by Charalambos A. Charalambides and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-06-24 with Mathematics categories.


A unique approach illustrating discrete distribution theory throughcombinatorial methods This book provides a unique approach by presenting combinatorialmethods in tandem with discrete distribution theory. This method,particular to discreteness, allows readers to gain a deeperunderstanding of theory by using applications to solve problems.The author makes extensive use of the reduction approach toconditional distributions of independent random occupancy numbers,and provides excellent studies of occupancy and sequentialoccupancy distributions, convolutions of truncated discretedistributions, and compound and mixture distributions. Combinatorial Methods in Discrete Distributions begins with abrief presentation of set theory followed by basic countingprinciples. Fundamental principles of combinatorics, finitedifferences, and discrete probability are included to give readersthe necessary foundation to the topics presented in the text. A thorough examination of the field is provided andfeatures: Stirling numbers and generalized factorial coefficients Occupancy and sequential occupancy distributions n-fold convolutions of truncated distributions Compound and mixture distributions Thoroughly worked examples aid readers in understanding complextheory and discovering how theory can be applied to solve practicalproblems. An appendix with hints and answers to the exercises helpsreaders work through the more complex sections. Reference notes areprovided at the end of each chapter, and an extensive bibliographyoffers readers a resource for additional information on specializedtopics.